Carbon Ion Radiotherapy for Unresectable Sacral Chordomas

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Carbon ion radiotherapy for unresectable sacral chordomas.

PURPOSE The purpose is to evaluate the efficacy and toxicity of carbon ion radiotherapy for unresectable sacral chordomas. EXPERIMENTAL DESIGN We performed a retrospective analysis of 30 patients with unresectable sacral chordomas treated with carbon ion radiotherapy at the Heavy Ion Medical Accelerator in Chiba, Japan. Twenty-three patients presented with no prior treatment, and the remainin...

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BACKGROUND Sacral chordoma (SC) is a neoplasm arising from residual notochordal cells degeneration. SC is difficult to manage mainly because of anatomic location and tendency to extensive spread. Carbon ion radiotherapy (CIRT) is highly precise to selectively deliver high biological effective dose to the tumor target sparing the anatomical structure on its path even if when SC is contiguous to ...

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ژورنال

عنوان ژورنال: Clinical Cancer Research

سال: 2004

ISSN: 1078-0432,1557-3265

DOI: 10.1158/1078-0432.ccr-04-0301